Related Experiment Video
Updated: Jun 8, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Skin rejuvenation with intense pulsed light
Elisabeth A Kohl1, Philipp Babilas, Michael Landthaler
1Department of Dermatology, Regensburg University Hospital, Franz-Josef-Strauss-Allee 11, Regensburg, Germany.
Nonablative skin rejuvenation using infrared lasers is popular for treating hyperpigmentation, telangiectasias, and erythema. While effective for these conditions, results for wrinkle treatment are less favorable compared to ablative therapies.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Laser and Light Therapies
Background:
- Skin rejuvenation is a leading dermatological application for laser and intense pulsed light (IPL) treatments.
- Nonablative skin rejuvenation utilizing infrared lasers has gained significant traction in recent years.
- Patient demand for minimally invasive cosmetic procedures continues to rise.
Purpose of the Study:
- To evaluate the efficacy of nonablative infrared laser treatments for various skin rejuvenation indications.
- To compare the outcomes of nonablative therapy with ablative methods for specific skin concerns.
- To provide insights into the current standing of nonablative laser treatments in cosmetic dermatology.
Main Methods:
- Review of current literature on nonablative infrared laser skin rejuvenation.
- Analysis of treatment outcomes for conditions such as hyperpigmentation, telangiectasias, erythema, and wrinkles.
- Comparison of efficacy data between nonablative and ablative laser/light-based therapies.
Main Results:
- Nonablative infrared laser treatments demonstrate excellent results for correcting hyperpigmentation, telangiectasias, and erythema.
- The effectiveness of nonablative therapy in treating wrinkles is notably less pronounced than that achieved with ablative treatments.
- Patient satisfaction is generally high for vascular and pigmentary conditions.
Conclusions:
- Nonablative infrared lasers are highly effective for specific skin rejuvenation goals, particularly pigmentary and vascular issues.
- For significant wrinkle reduction, ablative therapies remain the gold standard, offering more substantial collagen remodeling.
- Further research may explore combination therapies or advancements to enhance nonablative wrinkle treatment outcomes.
More Related Videos
Related Concept Videos
Renewal of Skin Epidermal Stem Cells
Tissue Renewal without Stem Cells
However, failure of such a system...
Acne Infection

