'Living' controlled in situ gelling systems: thiol-disulfide exchange method toward tailor-made biodegradable
De-Cheng Wu1, Xian Jun Loh, Yun-Long Wu
1Institute of Materials Research and Engineering, Agency for Science, Technology and Research, 3 Research Link, Singapore 117602. dc-wu@imre.a-star.edu.sg
Journal of the American Chemical Society
|October 9, 2010
Abstract:
A 'living' controlled hydrogel formation method was first reported to create loose and compact in situ biodegradable hydrogels. The method executed under mild reaction conditions can conveniently tailor the hydrogel properties, and it has the potential to develop into a powerful tool for the design, synthesis, and self-assembly of novel tailor-made biomaterials and drug delivery systems.
