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Proteus syndrome.

S Criton1, P A Majeed, P U Asokan

  • 1Departments of Dermato-Venereology, and Medicine, Medical College Hospital, Velappaya-680596, India, .

Indian Journal of Dermatology, Venereology and Leprology
|October 19, 2010
PubMed
Summary
This summary is machine-generated.

Proteus syndrome, a hamartomatous disorder causing overgrowths, can affect any body structure. This case study describes an eleven-year-old girl with Proteus syndrome presenting with clitoromegaly.

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Area of Science:

  • Medical Genetics
  • Pediatric Endocrinology
  • Dermatology

Background:

  • Proteus syndrome is a rare congenital hamartomatous disorder.
  • It is characterized by asymmetric, mosaic overgrowths affecting various body tissues.
  • The genetic basis and precise pathogenesis remain incompletely understood.

Purpose of the Study:

  • To report a case of Proteus syndrome in an eleven-year-old girl.
  • To highlight the manifestation of clitoromegaly in this pediatric patient with Proteus syndrome.

Main Methods:

  • Case report presentation.
  • Clinical examination and diagnostic assessment of an eleven-year-old female patient.

Main Results:

  • The patient was diagnosed with Proteus syndrome.
  • A significant finding in this case was the presence of clitoromegaly.

Conclusions:

  • Proteus syndrome can present with diverse clinical manifestations, including genital abnormalities.
  • This case underscores the importance of recognizing Proteus syndrome in pediatric patients with unusual overgrowths.
  • Further research is needed to elucidate the full spectrum of Proteus syndrome and its management.