[Amyloid arthropathy associated with multiple myeloma]
J Rodríguez Ramírez1, M Antúnez Díaz, P Peña Quintana
1Departamento de Anatomía Patológica, Hospital Insular, Las Palmas de Gran Canaria.
Anales De Medicina Interna (Madrid, Spain : 1984)
|March 1, 1990
Summary
Amyloidosis is a rare complication of multiple myeloma, especially in the joints, mimicking rheumatoid arthritis. This case highlights amyloid arthritis linked to Bence-Jones myeloma.
Area of Science:
- Rheumatology
- Hematology
- Pathology
Background:
- Multiple myeloma is a plasma cell malignancy.
- Amyloidosis is a known complication of multiple myeloma, occurring in approximately 15% of cases.
- Articular involvement in amyloidosis secondary to multiple myeloma is exceptionally rare.
Observation:
- A specific case of amyloid arthritis associated with Bence-Jones myeloma is presented.
- The patient's clinical presentation mimicked rheumatoid arthritis.
- The amyloid deposition was identified as kappa light chain type.
Findings:
- The presented case underscores the diagnostic challenge of amyloid arthritis.
- Early identification of amyloidosis in multiple myeloma patients is crucial.
- Kappa light chain amyloidosis can manifest with articular symptoms.
Implications:
- This case contributes to the understanding of rare myeloma complications.
- Highlights the importance of considering amyloidosis in myeloma patients with joint pain.
- Further research into early diagnostic markers for amyloid arthritis is warranted.
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