Related Experiment Video

Updated: Aug 8, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

[Amyloid arthropathy associated with multiple myeloma]

J Rodríguez Ramírez1, M Antúnez Díaz, P Peña Quintana

  • 1Departamento de Anatomía Patológica, Hospital Insular, Las Palmas de Gran Canaria.

Anales De Medicina Interna (Madrid, Spain : 1984)
|March 1, 1990
PubMed

Insights

Amyloidosis is a rare complication of multiple myeloma, especially in the joints, mimicking rheumatoid arthritis. This case highlights amyloid arthritis linked to Bence-Jones myeloma.

Area of Science:

  • Rheumatology
  • Hematology
  • Pathology

Background:

  • Multiple myeloma is a plasma cell malignancy.
  • Amyloidosis is a known complication of multiple myeloma, occurring in approximately 15% of cases.
  • Articular involvement in amyloidosis secondary to multiple myeloma is exceptionally rare.

Observation:

  • A specific case of amyloid arthritis associated with Bence-Jones myeloma is presented.
  • The patient's clinical presentation mimicked rheumatoid arthritis.
  • The amyloid deposition was identified as kappa light chain type.

Findings:

  • The presented case underscores the diagnostic challenge of amyloid arthritis.
  • Early identification of amyloidosis in multiple myeloma patients is crucial.
  • Kappa light chain amyloidosis can manifest with articular symptoms.

Implications:

  • This case contributes to the understanding of rare myeloma complications.
  • Highlights the importance of considering amyloidosis in myeloma patients with joint pain.
  • Further research into early diagnostic markers for amyloid arthritis is warranted.

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