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Retinal macroaneurysm associated with ocular sarcoidosis
Katsutoshi Yokoi1, Masayo Oshita, Hiroshi Goto
1Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan. katsyokoi@yahoo.co.jp
Japanese Journal of Ophthalmology
|November 6, 2010
Summary
Retinal macroaneurysm, a rare complication of ocular sarcoidosis, often presents bilaterally and with multiple lesions, differing from non-sarcoid forms.
Area of Science:
- Ophthalmology
- Rheumatology
- Immunology
Background:
- Ocular sarcoidosis is an inflammatory condition affecting the eye.
- Retinal macroaneurysm is a rare vascular complication.
- This study investigates the specific characteristics of retinal macroaneurysm in sarcoidosis patients.
Purpose of the Study:
- To characterize retinal macroaneurysm as a complication of ocular sarcoidosis.
- To compare its features with non-sarcoid related retinal macroaneurysm.
Main Methods:
- Retrospective analysis of 97 sarcoidosis patients with intraocular inflammation.
- Data collected from Tokyo Medical University Hospital Uveitis Clinic (1997-2006).
Main Results:
- Retinal macroaneurysm occurred in 7.2% of patients (7/97).
- Mean age at onset was 61 years.
- Lesions were more frequent in the chronic phase of sarcoidosis.
- High rates of bilateral (29%) and multiple (56%) lesions were observed, unlike typical solitary, unilateral presentations.
Conclusions:
- Retinal macroaneurysm associated with ocular sarcoidosis exhibits distinct clinical features.
- These features differ significantly from macroaneurysm not linked to sarcoidosis.
