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Fabrication of carbohydrate microarrays through boronate formation

Hsuan-Yi Hsiao1, Mu-Lin Chen, Huan-Ting Wu

  • 1Department of Chemistry, National Tsing-Hua University, Hsinchu, Taiwan.

Chemical Communications (Cambridge, England)
|November 27, 2010
PubMed

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DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...