Sample motion-insensitive, full-range, complex, spectral-domain optical-coherence tomography
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Updated: Jun 6, 2026

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
Published on: October 2, 2021
Stefan Zotter1, Michael Pircher, Erich Götzinger
1Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währingerstrasse 13, A-1090 Vienna, Austria. stefan.zotter@meduniwien.ac.at
Abstract:
We present a full-range, complex, spectral-domain optical-coherence-tomography (SD-OCT) system that is based on a double-beam scanning approach. The sample beams of two identical SD-OCT setups are combined collinearly by a bulk optic beam splitter before illuminating the object. The required phase shift for the complex signal reconstruction comes from the phase difference between both interferometers. Because of the double-beam scanning approach, our system is completely insensitive to sample motion. To demonstrate the performance of our setup, we present images of the human optic nerve head in vivo and of a human tooth.
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