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Updated: Jun 6, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
The importance of pursuing a histological diagnosis in the HIV setting
K A Fernando1, S Acharya, J T Arumaninayagam
1Walsall Centre for Sexual Health, Walsall Hospitals NHS Trust, Pleck Road, Walsall WS2 7BR, UK. kafernando@hotmail.com.
Abstract:
A 40-year-old heterosexual African man was admitted with fever, night sweats and lymphadenopathy. His human immunodeficiency virus antibody test was positive. Initial lymph node biopsy revealed reactive hyperplasia only. He was empirically treated for tuberculosis. However, symptoms persisted and a repeat lymph node biopsy was obtained, which confirmed Hodgkin's disease. This emphasises the need to pursue histological diagnosis in such patients with persisting symptoms.
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