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Identification of a novel HLA-A*26 allele, A*26:36, by sequence-based typing

J-P Li1, X-F Li, Y Chen

  • 1Liaoning Blood Center, HLA Typing Lab, Shenyang, Liaoning, China.

Tissue Antigens
|January 11, 2011
PubMed

Abstract:

The novel HLA (human leukocyte angiten)-A*26 allele differs from A*26:01:01 by a single nucleotide substitution at position 292 of exon 2 where a 'G' change to 'C'.

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
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