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Updated: Jun 5, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
15:54

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

X chromosome inactivation and embryonic stem cells

Tahsin Stefan Barakat1, Joost Gribnau

  • 1Department of Reproduction and Development, University Medical Center, Room Ee 09-71, Erasmus MC, 3015 GE, Rotterdam, Netherlands.

Advances in Experimental Medicine and Biology
|January 12, 2011
PubMed
Summary

X chromosome inactivation (XCI) equalizes gene dosage in females. This chapter explores XCI regulators, initiation models, and chromatin changes, using stem cells to study this essential process.

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