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Updated: Jun 5, 2026

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction
12:38

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction

Published on: August 9, 2011

Atomic-level modelling of the HIV capsid.

Owen Pornillos1, Barbie K Ganser-Pornillos, Mark Yeager

  • 1Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.

Nature
|January 21, 2011
PubMed
Summary

Researchers determined the X-ray structure of the human immunodeficiency virus type 1 (HIV-1) pentamer, revealing subtle rearrangements and an electrostatic switch controlling capsid assembly. This work enables atomic-level modeling of the complete HIV-1 capsid.

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