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Updated: Jun 5, 2026

Oral Biofilm Formation on Different Materials for Dental Implants
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Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Nanotechnology and dental implants.

Sandrine Lavenus1, Guy Louarn, Pierre Layrolle

  • 1Inserm U957, Bone Resorption Physiopathology and Primary Bone Tumors Therapy, Faculty of Medicine, University of Nantes - 1 rue Gaston Veil, 44035 Nantes cedex 1, France.

International Journal of Biomaterials
|January 22, 2011
PubMed
Summary
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Dental implant success hinges on early osseointegration. Surface nanotechnologies and calcium phosphate coatings enhance bone healing and implant stability for better clinical outcomes.

Area of Science:

  • Biomaterials Science
  • Dental Implantology
  • Tissue Engineering

Background:

  • Long-term dental implant success depends on early osseointegration, the direct bone-to-implant contact.
  • Implant surfaces interact with blood proteins, platelets, and mesenchymal stem cells, influencing peri-implant tissue healing.
  • Surface properties like chemistry and roughness critically affect biological interactions and cellular responses.

Purpose of the Study:

  • To review the biological interactions occurring at the implant-tissue interface.
  • To explore the role of surface properties, particularly at the nanoscale, in enhancing osseointegration.
  • To discuss the application of nanotechnologies and calcium phosphate coatings for improved dental implant performance.

Main Methods:

  • Review of scientific literature on dental implant osseointegration.

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  • Analysis of the influence of surface physicochemical properties on cellular and tissue responses.
  • Examination of nanotechnological surface modifications and calcium phosphate coatings.

    • Main Results:

    • Nanoscale surface features control protein adsorption, cell adhesion, and differentiation, crucial for osseointegration.
    • Calcium phosphate (CaP) nanocrystal coatings are bioactive, resorbable, and stimulate bone apposition.
    • Surface modifications significantly impact the biological interactions essential for stable bone-implant anchoring.

    Conclusions:

    • Nanotechnologies offer promising strategies for tailoring dental implant surfaces to promote optimal osseointegration.
    • Bioactive CaP coatings enhance bone healing and contribute to improved clinical success rates.
    • Future advancements in nanometer-controlled surfaces hold potential for directing peri-implant tissue development and maximizing implant longevity.