Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoluminescence: Applications

Photoluminescence: Applications

Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Multi-Regional Single-nucleus Atlas of the Huntington's Disease Brain.

Scientific data·2026

Same author

DPPA inhibits melanoma by targeting angiogenesis through activating autocrine IFN-γ-CXCL9/10/11-CXCR3 axis in vascular endothelial cells.

iScience·2026

Same author

Discovery of Potent and Selective Benzothiophene Difluoromethyl Phosphonate (DFMP) PTPN2/N1-Dual Inhibitors.

Journal of medicinal chemistry·2026

Same author

A COF-decorated nanocellulose separator affording modulated ion transport for advanced Zn metal batteries.

Chemical communications (Cambridge, England)·2026

Same author

Single-nucleus transcriptomics of an engineered pig model reveals microglia-T cell interactions driving Huntington's disease neurodegeneration.

Nature biomedical engineering·2026

Same author

Emerging insights into enhancer RNAs: biogenesis, function, mechanism, and disease implication.

Briefings in bioinformatics·2026

Same journal

Direct air capture technologies: innovations, integration, and pathways to scale.

Chemical Society reviews·2026

Same journal

Fluorescent merocyanines: from fundamental properties to applications as molecular probes, in bioimaging and as emissive dye aggregates.

Chemical Society reviews·2026

Same journal

Direct impure water electrolysis at industrial scale.

Chemical Society reviews·2026

Same journal

Catalytic valorization of polyolefins: from catalysts and processes to reactors.

Chemical Society reviews·2026

Same journal

Designing stable π-radicals.

Chemical Society reviews·2026

Same journal

Antibacterial drug discovery: challenges and preclinical promises from synthetic small molecules.

Chemical Society reviews·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

Published on: March 9, 2017

Phosphorescent heavy-metal complexes for bioimaging.

Qiang Zhao¹, Chunhui Huang, Fuyou Li

¹Department of Chemistry & Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, P. R. China.

Chemical Society Reviews

|January 22, 2011

Summary

This summary is machine-generated.

Phosphorescent heavy-metal complexes offer unique advantages for bioimaging applications. This review highlights their photophysical properties, cellular interactions, and diverse imaging capabilities, paving the way for future advancements.

More Related Videos

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II

Published on: July 7, 2015

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems

Published on: March 3, 2010

Related Experiment Videos

Last Updated: Jun 5, 2026

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

Published on: March 9, 2017

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II

Published on: July 7, 2015

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems

Published on: March 3, 2010

Area of Science:

Coordination Chemistry
Biomedical Imaging
Materials Science

Background:

Phosphorescent heavy-metal complexes are emerging as powerful tools in bioimaging.
Their unique photophysical properties offer advantages over traditional fluorescent probes.
Heavy-metal complexes with d(6), d(8), and d(10) electron configurations are of particular interest.

Purpose of the Study:

To systematically review the advantages of phosphorescent heavy-metal complexes as bioimaging probes.
To summarize the progress in their application for various bioimaging techniques.
To discuss future research directions in this promising field.

Main Methods:

Literature review of phosphorescent heavy-metal complexes for bioimaging.
Evaluation of their photophysical properties, cytotoxicity, and cellular uptake.
Analysis of their application in cellular staining, intracellular monitoring, and targeted imaging.

Main Results:

Phosphorescent heavy-metal complexes exhibit desirable photophysical properties for bioimaging.
Their cellular uptake mechanisms and cytotoxicity profiles are crucial for probe design.
Successful applications include staining, monitoring, targeted, two-photon, small-animal, multimodal, and time-resolved bioimaging.

Conclusions:

Phosphorescent heavy-metal complexes represent a significant advancement in bioimaging probe development.
Further research into their design and application will enhance their utility in biological studies.
This field holds great promise for future innovations in medical diagnostics and research.