Related Experiment Video
Updated: Jun 4, 2026
03:47
Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Fractionated CO2 laser skin rejuvenation
Emily P Tierney1, Richard F Eisen, C William Hanke
1Boston University School of Medicine, Boston, Massachusetts, USA. etierney29@gmail.com
Dermatologic Therapy
|February 1, 2011
Summary
Fractional laser resurfacing, including non-ablative fractional laser (NAFL) and ablative fractional laser (AFL), effectively treats photoaging. These advanced treatments offer significant improvements over older methods with fewer side effects.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Laser Technology
Background:
- Photoaging presents significant challenges in skin texture and pigmentation.
- Fractional photothermolysis has emerged as a promising therapeutic approach.
Purpose of the Study:
- To review existing literature on non-ablative fractional laser (NAFL) and ablative fractional laser (AFL) for treating photoaging.
- To evaluate the safety and efficacy of these fractional laser modalities.
Main Methods:
- A comprehensive review of Medline literature was conducted.
- Studies focusing on NAFL and AFL for photoaging treatment were analyzed.
Main Results:
- Literature review supports the use of both NAFL and AFL as safe and effective treatments for photoaging.
- Fractional resurfacing demonstrates controlled dermal heating, potentially normalizing collagenesis/collagenolysis.
Conclusions:
- Fractional laser resurfacing represents a significant advancement in photoaging treatment.
- NAFL and AFL offer improved outcomes with reduced complications compared to traditional ablative laser resurfacing.
Related Concept Videos
01:16Confocal Fluorescence Microscopy
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
01:12Renewal of Skin Epidermal Stem Cells
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...