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A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
A case of superficial angiomyxoma
Kozo Yamamoto1, Akio Kondo, Kenichi Iwashita
1Department of Dermatology, Course of Specialized Clinical Sciense, Tokai University School of Medicine, Bohseidai, Isehara-shi, Kanagawa 259-1193, Japan. kozokayo@qd5.so-net.ne.jp
Abstract:
We report a case of a 19-year-old man who showed a brownish, elastic-soft, multilocular, pedunculated, solid tumor (10 × 6 × 6 cm), with scale crust and erosion, on the medial side of the right thigh. The histopathology of a specimen removed completely revealed a tumor that was located between the middle layer of the dermis and the subcutaneous fatty tissue, was filled with a mucoid material, and was surrounded by a fibrous tissue. The tumor consisted of small thin-walled blood vessels and spindle-shaped or stellate tumor cells without cytological atypia in addition to the mucoid material. Immunohistochemistory revealed that the tumor cells express the vimentin stain. Based on these clinical and histologic findings, we diagnosed the skin condition as superficial angiomyxoma.