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Updated: Aug 9, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
[Reflections on the anterior cruciate ligament (A.C.L.) and clinical implications]
1Chirurgien-orthopédiste, Clinique Hubert, Dakar.
Abstract:
This report documents experiments on the front, crossed ligament undertaken after dissection of 17 human knees. The form, direction, constitution, and even the various diameters and tibial and femoral bone insertion surfaces of the ligament were all studied. Various cross-section experiments were undertaken to reveal the physio-pathological aspects. Greater tibial insertion area and diameter along with a more oblique orthogonal projection on the tibial correspond to the need to better spread the constraints. It is concluded that varying degrees of tension in function of the position of the knee, and knowledge of the various lengths and diameters of the ligament permit a better understanding of the prosthetic replacement surgery required.
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