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Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
Epidemiology of IBS.
Rok Seon Choung1, G Richard Locke
1Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Irritable bowel syndrome (IBS), a common functional gastrointestinal disorder, affects about 10% of the population. Studies show IBS is more prevalent in younger females and often co-occurs with other non-GI symptoms.
Area of Science:
- Gastroenterology
- Epidemiology
Background:
- Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder.
- Understanding IBS epidemiology requires population-based studies due to varying healthcare-seeking behaviors.
Purpose of the Study:
- To present the epidemiology of IBS.
- To highlight key demographic and clinical features of IBS patients.
Main Methods:
- Population-based epidemiological study.
- Analysis of incidence and prevalence data.
Main Results:
- Approximately 10% of the population experiences IBS at any given time.
- Annual incidence of new IBS diagnoses is around 200 per 100,000 individuals.
- IBS is more common in younger individuals, with a notable female predominance in Western countries and specialized care settings.
- Patients with IBS frequently report concurrent upper gastrointestinal and various non-gastrointestinal symptoms.
Conclusions:
- IBS is a widespread condition with significant demographic and clinical characteristics.
- The findings underscore the importance of considering IBS in differential diagnoses, especially in younger females presenting with GI and non-GI complaints.
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