Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sites for measuring blood pressure01:21

Sites for measuring blood pressure

Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"Chronic Cervical Midline Contusion in Rats Disrupts Aerobic, Muscular, and Cardiovascular Function".

bioRxiv : the preprint server for biology·2025
Same author

Efficacy of a mephentermine-based product as a vasopressor and a cardiac performance enhancer when given intramuscularly to cattle.

Journal of veterinary pharmacology and therapeutics·2017
Same author

An overview of the safety pharmacology career of Dr. C.R. Hassler.

Journal of pharmacological and toxicological methods·2017
Same author

The safety of high-dose buprenorphine administered subcutaneously in cats.

Journal of veterinary pharmacology and therapeutics·2015
Same author

PATHWAYS OF VENTRICULAR DEPOLARIZATION IN VARIOUS SPECIES.

A listing of research in the cardiovascular field·2014
Same author

Effects of chronic, oral amiodarone on left ventricular pressure, electrocardiograms, and action potentials from myocardium in vivo and from Purkinje fibers in vitro.

Veterinary therapeutics : research in applied veterinary medicine·2009

Related Experiment Video

Updated: Jun 4, 2026

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
09:56

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Published on: February 14, 2021

Measuring high pressure baroreceptor sensitivity in the rat.

L J Shiry1, R L Hamlin

  • 1QTest Labs, LLC, Department of Veterinary Biosciences, The Ohio State University, United States.

Journal of Pharmacological and Toxicological Methods
|February 23, 2011
PubMed
Summary
This summary is machine-generated.

This study introduces a new method to monitor the baroreceptor reflex in rats, assessing both heart rate and blood pressure changes. The technique effectively detected blunted baroreceptor function under specific anesthetic and pretreatment conditions.

More Related Videos

Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats
07:35

Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats

Published on: January 31, 2019

Measurement of Pulmonary Artery Pressure in Rats Using Right Heart Catheterization
07:21

Measurement of Pulmonary Artery Pressure in Rats Using Right Heart Catheterization

Published on: December 16, 2025

Related Experiment Videos

Last Updated: Jun 4, 2026

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
09:56

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Published on: February 14, 2021

Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats
07:35

Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats

Published on: January 31, 2019

Measurement of Pulmonary Artery Pressure in Rats Using Right Heart Catheterization
07:21

Measurement of Pulmonary Artery Pressure in Rats Using Right Heart Catheterization

Published on: December 16, 2025

Area of Science:

  • Physiology
  • Cardiovascular Research
  • Animal Models

Background:

  • The baroreceptor reflex is crucial for regulating blood pressure and heart rate.
  • Drug-induced alterations in this reflex can lead to adverse events, especially in older adults.
  • Current methods for assessing baroreceptor function can be improved for greater accuracy and clinical relevance.

Purpose of the Study:

  • To develop and validate a facile method for monitoring the high-pressure baroreceptor reflex in rats.
  • To quantify the baroreceptor reflex using both heart rate and systemic arterial pressure changes.
  • To investigate the impact of different anesthetics and aldosterone pretreatment on baroreceptor function.

Main Methods:

  • Twenty-four rats were divided into three groups based on anesthesia (thiopental or isoflurane) or aldosterone pretreatment.
  • A controlled negative pressure was applied to the carotid artery region to stimulate the baroreceptor reflex.
  • Systemic arterial pressure, ECG, heart rate, and suction force were continuously recorded.

Main Results:

  • Neck suction induced significant changes in heart rate and systemic arterial pressure in rats anesthetized with thiopental.
  • Rats anesthetized with isoflurane or pretreated with aldosterone showed minimal changes in heart rate and blood pressure, indicating blunted baroreceptor function.
  • The study established ratios for changes in heart rate and blood pressure relative to the applied negative pressure.

Conclusions:

  • The developed methodology effectively detects blunting of baroreceptor reflex function in rats.
  • This technique offers a more comprehensive assessment of baroreceptor reflex by measuring both heart rate and blood pressure.
  • The findings highlight the influence of anesthetic agents and aldosterone on baroreceptor reflex sensitivity.