Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vacuolar and ER-Ca2+-ATPases regulate calcium dynamics during pollen tube growth in Arabidopsis thaliana.

Plant physiology·2026
Same author

New Perspectives Provided by Merging Computed Tomographic Scanning and Electroanatomical Mapping of Koch's Pyramid.

Journal of cardiovascular development and disease·2026
Same author

Phantom for standardization in functional near-infrared spectroscopy, part 2: optical properties and Monte Carlo simulations.

Neurophotonics·2026
Same author

Amplitude- and Phase-Programmable Dual-Color Photonic Chip for High-Contrast Structured Illumination Microscopy.

ACS photonics·2026
Same author

MAcro Plant Projection Imaging (MAPPI): An open, scalable platform for whole-plant fluorescence real-time imaging.

Science advances·2026
Same author

In-vivo optical properties spectra across five body locations on ten subjects using time-domain diffuse optics.

Scientific data·2026
Same journal

Generalizable framework for multi-site bone density prediction using non-dominant wrist optical biomarkers.

Biomedical optics express·2026
Same journal

Erratum: Review of dynamic optical coherence tomography for intracellular motility [Invited]: errata.

Biomedical optics express·2026
Same journal

Digital-micromirror-device-based illumination strategies for background suppression in single-molecule localization microscopy.

Biomedical optics express·2026
Same journal

Synergistic combination of convective self-assembly and hollow core fiber for sensitive SERS detection of glucose molecules.

Biomedical optics express·2026
Same journal

Multimodal diagnostic network integrating infrared and mass spectra for lung cancer.

Biomedical optics express·2026
Same journal

Multimodal Optical Biosensing for Precision Medicine and Healthcare: Introduction to the feature issue.

Biomedical optics express·2026
See all related articles

Related Experiment Video

Updated: Jun 3, 2026

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph
05:32

Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph

Published on: February 21, 2025

Functional tomography using a time-gated ICCD camera.

Qing Zhao, Lorenzo Spinelli, Andrea Bassi

    Biomedical Optics Express
    |March 18, 2011
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel near-infrared functional tomography system for non-contact brain imaging. The system uses time-gated photon detection to achieve depth and spatial localization for functional studies.

    Keywords:
    (170.3890) Medical optics instrumentation(170.5280) Photon migration(170.6920) Time-resolved imaging

    More Related Videos

    Time-resolved Photophysical Characterization of Triplet-harvesting Organic Compounds at an Oxygen-free Environment Using an iCCD Camera
    06:08

    Time-resolved Photophysical Characterization of Triplet-harvesting Organic Compounds at an Oxygen-free Environment Using an iCCD Camera

    Published on: December 27, 2018

    Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
    12:24

    Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

    Published on: July 17, 2012

    Related Experiment Videos

    Last Updated: Jun 3, 2026

    Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph
    05:32

    Retrospective Cardiac Gating with A Prototype Small-Animal X-ray Computed Tomograph

    Published on: February 21, 2025

    Time-resolved Photophysical Characterization of Triplet-harvesting Organic Compounds at an Oxygen-free Environment Using an iCCD Camera
    06:08

    Time-resolved Photophysical Characterization of Triplet-harvesting Organic Compounds at an Oxygen-free Environment Using an iCCD Camera

    Published on: December 27, 2018

    Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
    12:24

    Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

    Published on: July 17, 2012

    Area of Science:

    • Biomedical Optics
    • Medical Imaging Technology
    • Neuroimaging

    Background:

    • Near-infrared functional tomography (fNIRS) is a valuable tool for non-invasive brain imaging.
    • Current fNIRS systems face challenges in achieving accurate depth information and spatial resolution.
    • Non-contact measurement capabilities are desirable for improved patient comfort and broader applicability.

    Purpose of the Study:

    • To develop and validate a novel near-infrared functional tomography system.
    • To enable non-contact, large-area photon collection for enhanced data acquisition.
    • To improve depth and lateral localization capabilities for functional brain imaging.

    Main Methods:

    • Utilized a single pulsed near-infrared light source and a time-gated camera.
    • Employed time-encoded data analysis to determine photon penetration depth.
    • Leveraged photon exit point for lateral localization of optical perturbations.
    • Validated the system through simulations and preliminary phantom measurements.

    Main Results:

    • Demonstrated successful detection and localization of optical perturbations in simulations.
    • Achieved good detection sensitivity for low optical perturbations in phantom studies.
    • Showcased localization capabilities, with spatial resolution decreasing at greater depths.
    • Confirmed the principle that photon arrival time, not source-detector distance, dictates penetration depth.

    Conclusions:

    • The developed time-gated near-infrared functional tomography system shows promise for non-contact functional brain imaging.
    • The method effectively utilizes photon arrival time for depth encoding and exit point for lateral localization.
    • Further development is needed to optimize spatial resolution for deeper targets in potential in vivo applications.