[Directional differentiation of adipose-derived stem cell]

Adipose-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) derived from adipose tissue, which have the ability to self-renew and differentiate into many types of tissues. Here we summarize the recent advances in the research of ADSCs, introduce the methods of ADSCs isolation and culture, and discusse the factors regulating the adipo-differentiation and osteo-differentiation of ADSCs. The present review will yield novel insight relevant to the therapeutic intervention of obesity and osteo-tissue engineering.