Related Experiment Video
Updated: Jun 3, 2026
09:36
Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
Adverse consequences of acute inhalant intoxication.
Eric L Garland1, Matthew O Howard
1Trinity Institute for the Addictions, College of Social Work, Tallahassee, FL, USA. egarland@fsu.edu
Experimental and Clinical Psychopharmacology
|April 6, 2011
Summary
Adolescent inhalant misuse is common and linked to severe risks. High-frequency inhalant users and those using inhalants for self-medication face greater adverse consequences and high-risk behaviors.
Area of Science:
- Substance Abuse Research
- Adolescent Psychology
- Public Health
Background:
- Inhalant misuse is prevalent among adolescents, posing significant toxicity risks.
- Acute inhalant intoxication can lead to dangerous behaviors and adverse outcomes.
Purpose of the Study:
- To investigate the prevalence of adverse consequences from acute inhalant intoxication in adolescents.
- To identify correlates of these adverse experiences and high-risk behaviors.
Main Methods:
- Structured interviews with 279 adolescent inhalant users in residential care.
- Multivariate logistic, linear regression, and path analyses to identify correlates.
Main Results:
- Adverse outcomes and high-risk behaviors during inhalant intoxication were common.
- High-frequency inhalant users exhibited significantly more adverse consequences.
- Engaging in unprotected sex or violence while intoxicated was more frequent in high-frequency users.
- Trauma history, impulsivity, self-medication, and polydrug use correlated with adverse consequences.
Conclusions:
- Adolescent inhalant intoxication frequently involves adverse events and risky behaviors.
- High-frequency use and self-medication of inhalants elevate the risk for negative outcomes.
More Related Videos
Related Concept Videos
01:20Inhalational Anesthetics: Overview
Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
01:25Inhalation Anthrax
Anthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium. It primarily affects herbivorous animals but can be transmitted to humans through skin contact, ingestion, or inhalation of spores.Cutaneous anthrax, the most common form, typically results from direct contact with bacterial spores through skin abrasions and is generally less severe. Gastrointestinal anthrax results from eating undercooked or contaminated meat. It affects the mouth, throat, or...
01:21Acute Respiratory Failure-I
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
01:23Acute Respiratory Failure-IV
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
01:30Acute Respiratory Failure-III
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without causing...
01:21Acute Respiratory Failure-II
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include: