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Updated: Jun 2, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
Diffusion magnetic resonance imaging in multiple sclerosis
L Celso Hygino da Cruz1, Raquel Ribeiro Batista, Roberto Cortes Domingues
1Clinics CDPI and Multi-Imagem, Rua Saddock de Sá 266, Rio de Janeiro, Brazil; Clinic IRM, Rua Capitao Salomao 44, Rio de Janeiro, Brazil; Department of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. celsohygino@hotmail.com
Abstract:
Multiple sclerosis (MS) is considered the most common inflammatory autoimmune neurologic disorder and the most frequent cause of nontraumatic neurologic disability in young and middle-age adults. This article reviews the basic features of its magnetic resonance (MR) imaging lesions and, primarily, the use of diffusion MR imaging, which is increasingly applied to assess patients with MS, not only to investigate plaques but also the normal-appearing white matter, gray matter, optic nerve, and spinal cord, because of its ability to detect and quantify disease-related pathologic conditions of the central nervous system.
Insights
Multiple sclerosis (MS) is a common neurologic disorder. Diffusion magnetic resonance (MR) imaging helps detect and quantify disease-related changes in the central nervous system, including lesions and normal-appearing tissues.
Area of Science:
- Neurology
- Radiology
- Immunology
Background:
- Multiple sclerosis (MS) is the most common inflammatory autoimmune neurologic disorder.
- It is a leading cause of nontraumatic neurologic disability in young and middle-aged adults.
Purpose of the Study:
- To review the basic features of magnetic resonance (MR) imaging lesions in MS.
- To highlight the increasing application of diffusion MR imaging in assessing MS patients.
Main Methods:
- Review of magnetic resonance (MR) imaging techniques for multiple sclerosis (MS).
- Focus on diffusion MR imaging applications.
- Assessment of lesions, normal-appearing white matter, gray matter, optic nerve, and spinal cord.
Main Results:
- Diffusion MR imaging is increasingly used in MS assessment.
- It can detect and quantify pathologic conditions in various CNS components.
- Provides insights beyond traditional lesion imaging.
Conclusions:
- Diffusion MR imaging offers valuable insights into MS pathology.
- Its application extends to various central nervous system (CNS) tissues.
- Enhances the comprehensive assessment of patients with multiple sclerosis (MS).
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