Related Experiment Video
Updated: Jun 1, 2026

Effect of Male Accessory Gland Products on Egg Laying in Gastropod Molluscs
Published on: June 22, 2014
Adhesion-GPCRs in the male reproductive tract
Ben Davies1, Christiane Kirchhoff
1Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN, UK. ben.davies@well.ox.ac.uk
Abstract:
The male reproductive tract expresses a diverse array of adhesion-GPCRs, many in a highly specific and regulated manner. Despite this specificity of expression, little is known about the function of this receptor family in male reproductive physiology. Insights into function are beginning to emerge with the increasing availability of genetically modified mice harbouring mutations in these genes. Gpr64 is the best characterised of the adhesion-GPCRs in the male reproductive system and the phenotype of Gpr64 knock-out mice implicates this receptor in the regulation of fluid absorption in the efferent ducts and proximal epididymis. This chapter summarizes recent data concerning this receptor and other family members in the male reproductive system.
Related Concept Videos
Accessory Glands of the Male Reproductive System
The epididymis is a small, comma-shaped organ located at the back of each testicle. The epididymis can be divided into three main parts: the head, body, and tail. The head of the epididymis...
Transducer Mechanism: G Protein–Coupled Receptors
GPCRs are also called heptahelical, 7TM, or...
G Protein-coupled Receptors
GPCRs are also called heptahelical, 7TM, or serpentine receptors, and consist of seven (H1-H7) transmembrane alpha-helices that span the bilayer to form a cylindrical core. The transmembrane helices are connected by three extracellular loops and three...
Accessory Ducts of the Male Reproductive System
The epididymis is a small, comma-shaped organ located at the back of each testicle.
GPCRs Regulate Adenylyl Cylase Activity
Two...
G-protein Coupled Receptors

