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Updated: Jun 1, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Use of antidepressants during pregnancy]
Lars Henning Pedersen1, Poul Videbech
1Gynækologisk-Obstetrisk Afdeling Y, Klinisk Institut, Aarhus Universitetshospital, Skejby, Denmark.
Abstract:
Pharmacological treatment of depression during pregnancy must balance the potential fetal risks of the medication with the risks of an undertreated or untreated depression. The choice of treatment is difficult and an increasing number of pregnant women and their doctors face the dilemma. There are non-pharmacological options for treatment but they may not be sufficient or available. The paper summarises the potential fetal effects of antidepressant use during pregnancy and attempts to put these effects in a clinical context.
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