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Related Experiment Video

Updated: May 31, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

The development and application of optogenetics.

Lief Fenno1, Ofer Yizhar, Karl Deisseroth

  • 1Department of Bioengineering, Stanford University, Stanford, California 94305, USA.

Annual Review of Neuroscience
|June 23, 2011
PubMed
Summary
This summary is machine-generated.

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Single-component optogenetic tools offer precise control over neural circuits, advancing neuroscience research. This review details their development and diverse applications across various model organisms.

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Genetics

Background:

  • Optogenetic tools allow for precise control of genetically defined cell populations.
  • Single-component tools simplify experimental design and implementation.
  • The rapid evolution of optogenetics offers expanding possibilities in neural research.

Purpose of the Study:

  • To review the development of current single-component optogenetic tools.
  • To summarize the applications of these tools in neuroscience research.
  • To highlight their use across diverse model organisms.

Main Methods:

  • Literature review of optogenetic tool development.
  • Compilation of studies utilizing single-component optogenetic tools.
  • Analysis of applications in various model systems.

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Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits
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Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse
05:50

Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse

Published on: February 12, 2020

Related Experiment Videos

Last Updated: May 31, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits
07:43

Laser-scanning Photostimulation of Optogenetically Targeted Forebrain Circuits

Published on: December 27, 2013

Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse
05:50

Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse

Published on: February 12, 2020

Main Results:

  • Overview of key single-component optogenetic tool advancements.
  • Examples of successful applications in understanding neural function.
  • Demonstration of tool versatility across species.

Conclusions:

  • Single-component optogenetic tools are crucial for modern neuroscience.
  • Their continued development broadens research scope and impact.
  • These tools facilitate significant progress in diverse biological models.