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Facile Access to an Efficient Solid-Supported Click Catalyst System Based on Poly(ethyleneimine)
Lies Bonami1, Wim Van Camp, Dieter Van Rijckegem
1Department of Organic Chemistry, Polymer Chemistry Research Group, Ghent University, Krijgslaan 281 S4 bis, B-9000 Ghent, Belgium.
Abstract:
A novel heterogeneous copper(I) catalyst system, which is based on readily available poly(ethyleneimine), has been used as a recyclable catalyst for Cu(I) catalyzed "click" 1,3 dipolar cycloaddition reactions of azides and alkynes in organic media. Branched poly(ethyleneimine) was first methylated and then cross-linked with 1,9-dibromononane. Subsequently, after the immobilization of Cu(I)Br, this system was applied for heterogeneous copper catalyzed click chemistry of a few model reagents and polymeric compounds.
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