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Phil Mitchell1, David Tollervey

  • 1Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK, p.j.mitchell@sheffield.ac.uk.

Advances in Experimental Medicine and Biology
|June 30, 2011
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Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...