Related Experiment Video
Updated: May 31, 2026
10:26
Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
Advances in local anesthesia in dentistry.
Orrett E Ogle1, Ghazal Mahjoubi
1Oral and Maxillofacial Surgery, Department of Dentistry, Woodhull Medical and Mental Health Center, 760 Broadway, Brooklyn, NY 11206, USA. Orrett.ogle@woodhullhc.nychhc.org
Dental Clinics of North America
|July 6, 2011
Summary
Recent advancements in dental local anesthesia agents and delivery technologies improve patient care. Innovations include new anesthetic agents, safety devices, and methods to reduce post-procedure numbness.
Area of Science:
- Dentistry
- Anesthesiology
- Pain Management
Background:
- Effective local anesthesia is paramount in dental patient care.
- Advances in anesthetic agents and delivery techniques represent significant progress in dental science.
Purpose of the Study:
- To provide an update on the latest local anesthetic agents and delivery technologies in dentistry.
- To discuss safety devices and innovative methods for mitigating post-anesthesia numbness.
Main Methods:
- Review of recently introduced local anesthetic agents.
- Discussion of new technologies for anesthetic delivery.
- Examination of safety devices and novel techniques for reducing lingering numbness.
Main Results:
- Introduction of novel local anesthetic formulations.
- Development of advanced delivery systems for enhanced efficacy and safety.
- Emergence of techniques to minimize prolonged sensory and motor deficits.
Conclusions:
- Continuous innovation in local anesthesia is crucial for improving dental patient outcomes.
- New agents, technologies, and methods enhance the safety and comfort of dental procedures.
- Addressing post-anesthetic numbness improves patient satisfaction and functional recovery.
Related Concept Videos
01:29Local Anesthetics: Clinical Application as Epidural Anesthesia
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
01:23Local Anesthetics: Common Agents and Their Applications
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
01:30Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
01:16Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
01:30Local Anesthetics: Chemistry and Structure-Activity Relationship
Local anesthetics (LAs) are drugs that induce a temporary loss of sensation in a limited body area, preventing pain. Cocaine was the first local anesthetic discovered in the late 19th century. Cocaine is a benzoic acid ester obtained from the leaves of coca shrubs and was often used for its psychotropic effects. Cocaine was first isolated in 1860 by Albert Niemann. Sigmund Freud studied the physiological actions of cocaine. Carl Koller later introduced it into clinical practice in 1884 as a...
01:11Local Anesthetics: Clinical Application as Spinal Anesthesia
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...