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Related Experiment Video

Updated: May 31, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

Published on: April 28, 2016

Developmental effects of ghrelin.

Sophie M Steculorum¹, Sebastien G Bouret

¹The Saban Research Institute, Neuroscience Program, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA 90027, USA.

|July 9, 2011

Summary

Ghrelin, a hormone regulating feeding and growth, also impacts perinatal development. Altered perinatal ghrelin levels can lead to lasting physiological changes and organ development differences.

Area of Science:

Endocrinology
Developmental Biology
Neuroscience

Background:

Ghrelin is recognized for its roles in adult feeding and growth hormone release.
Emerging evidence highlights ghrelin's significant influence during perinatal development.

Purpose of the Study:

To explore the developmental and organizational effects of ghrelin during the perinatal period.
To investigate the impact of ghrelin on early developmental events and organogenesis.

Main Methods:

Review of existing literature on ghrelin's perinatal actions.
Analysis of studies examining ghrelin's effects on blastocyst development, perinatal growth, and organ structure.
Examination of research on ghrelin's influence on early-life appetite centers.

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Last Updated: May 31, 2026

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

A RAPID Method for Blood Processing to Increase the Yield of Plasma Peptide Levels in Human Blood

Published on: April 28, 2016

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice

Published on: May 24, 2018

Fat Preference: A Novel Model of Eating Behavior in Rats

Fat Preference: A Novel Model of Eating Behavior in Rats

Published on: June 27, 2014

Main Results:

Perinatal ghrelin regulates key developmental events, including blastocyst development and overall growth.
Alterations in perinatal ghrelin levels are associated with structural modifications in organs like the pancreas and gastrointestinal tract.
Ghrelin influences appetite-related brain centers during early life.

Conclusions:

Ghrelin plays a crucial role in perinatal development, affecting organogenesis and physiological regulation.
Exposure to factors disrupting perinatal ghrelin signaling may result in long-term physiological consequences.
Understanding ghrelin's developmental impact is vital for addressing potential long-term health outcomes.