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Primary orbital Ewing sarcoma.

Yuli Yang¹, Yong Liu, Zhengqin Yin

¹Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, No. 30 Gaotanyan Main Street, Shapingba District, Chongqing 400038, China. yangyuli1979@yahoo.com.cn

Journal of Pediatric Ophthalmology and Strabismus

|July 20, 2011

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Primary orbital Ewing sarcoma is a rare male-predominant tumor. This case highlights its presentation, diagnosis using CD99 immunostaining, and treatment with surgery, radiotherapy, and chemotherapy.

Area of Science:

Oncology
Ophthalmology
Pathology

Background:

Primary orbital Ewing sarcoma is an exceptionally rare malignancy.
It predominantly affects males, with a reported ratio of 1.4:1.

Observation:

A 6-year-old boy presented with sudden vision loss and right proptosis.
CT imaging revealed an infratemporal orbital mass with lateral orbital wall erosion.
Surgical resection via anterior orbitotomy was performed.

Findings:

Histopathology showed CD99-positive tumor cells with a membranous pattern.
EWS-FLI-1 fusion gene was not detected by RT-PCR.
The tumor was classified as primary orbital Ewing sarcoma.

Implications:

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