Related Experiment Video
Updated: May 30, 2026

Analyzing the Functions of Mast Cells In Vivo Using 'Mast Cell Knock-in' Mice
Published on: May 27, 2015
[Advancement in researches of mast cell]
Shu-Hua Xiao1, Yang-Yang Liu, Lian-Hai Wei
1Center of Experimental Acupuncture, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Abstract:
Mast cells as the body's main immune cells, not only involved in allergic, inflammatory response, but also related to a lot of physiological and pathological processes. Its differentiation, maturation, activation and media release are in strict regulation and control. The in-depth study of mast cells not only allows us to understand the mechanism of allergy, inflammation and autoimmune diseases more thoroughly, but also provide us some valuable reference about the prevention and treatment of such diseases.
Related Concept Videos
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Inflammation
Mesenchymal Stem Cells

