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Updated: May 30, 2026

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
Published on: October 18, 2024
The surgical treatment of type two diabetes mellitus
Walter J Pories1, James H Mehaffey, Kyle M Staton
1Division of Bariatric Surgery, Department of Surgery, The Brody School of Medicine, East Carolina University, 600 Moye Boulevard, Brody Medical Science 4W-48, Mail Stop 639, Greenville, NC 27834, USA. pories@aol.com
Abstract:
Since the discovery that gastric bypass surgery leads to the rapid reversal of type 2 diabetes mellitus in morbidly obese patients, researchers have been searching for possible mechanisms to explain the result. The significance of bariatric surgery is twofold. It offers hope and successful therapy to the severely obese; those with T2DM, sleep apnea, or polycystic ovary disease; and others plagued by the comorbidities of the metabolic syndrome. This article examines four surgical procedures and their outcomes.
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