Related Experiment Video
Updated: May 30, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Urticaria multiforme--a case report
Lesley Starnes1, Tejesh Patel, Robert B Skinner
1Division of Dermatology, Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
Abstract:
The term "urticaria multiforme" has recently been proposed to replace acute annular urticaria and refers to a benign cutaneous hypersensitivity reaction characterized by the acute onset of large, polycyclic, and annular wheals with ecchymotic centers. It is associated with acral and facial angioedema, dermatographism, favorable response to antihistamines, and a self-limited course. It is most often mistaken for erythema multiforme and occasionally for serum sickness-like reaction. We report a case of urticaria multiforme in a 4-month-old infant, followed by a review of the literature.
Related Concept Videos
Hypersensitivity Reactions: Immune-Complex Reactions
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Drug Toxicity: Allergic Reactions
Allergic Reactions
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Allergic Reactions: Anaphylaxis
