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Updated: Aug 19, 2026

An Immunological Model for Heterotopic Heart and Cardiac Muscle Cell Transplantation in Rats
Published on: May 8, 2020
[Anesthesiologic problems of heart transplantation]
1Institut für Anästhesiologie, Universitätsspital, Zürich.
Abstract:
Although the risk of anaesthesia in patients undergoing cardiac transplantation is high, anaesthesia-related morbidity and mortality is extremely low, if management is based on adequate organ-preserving therapy, adaptation of anaesthetic techniques to the deranged myocardial function that characterizes end-stage cardiac disease, prevention of aspiration, reduction of the immunosuppression-induced risk of infection and consideration of the consequences of heart denervation. Problems associated with anaesthesia for surgery on post-cardiac transplant patients include adverse effects of immunsuppressive agents, and the particularities of the denervated heart with regard to haemodynamics and drug response.
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