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Related Concept Videos

Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
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Updated: May 30, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Published on: August 9, 2024

Primary dermatofibrosarcoma protuberans invading the orbit.

Jeff M Goshe1, Craig D Lewis, Jon G Meine

  • 1Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

Ophthalmic Plastic and Reconstructive Surgery
|August 2, 2011
PubMed
Summary
This summary is machine-generated.

Dermatofibrosarcoma protuberans, a rare skin cancer, can invade the orbit. Complete surgical excision, including orbital exenteration, achieved disease-free status in a unique orbital case.

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Area of Science:

  • Oncology
  • Dermatology
  • Ophthalmology
  • Surgical Pathology

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade malignant cutaneous neoplasm.
  • DFSP typically presents as a slow-growing, locally aggressive tumor with a high rate of recurrence.
  • Orbital involvement by primary DFSP is exceptionally rare, with limited documented cases.

Observation:

  • A 38-year-old male presented with a slow-growing, firm mass under the left eyebrow.
  • The tumor infiltrated orbital structures, including the medial canthal tendon and anterior orbital fat.

Findings:

  • Histopathology and immunohistochemistry confirmed DFSP.
  • Mohs micrographic surgery was insufficient for complete excision due to deep infiltration.
  • A successful margin-controlled excision, including exenteration and dacryocystectomy, was performed.

Implications:

  • This case highlights the potential for DFSP to arise primarily in the orbit.
  • Aggressive surgical management may be necessary for orbital DFSP.
  • Further research into DFSP orbital presentation and treatment is warranted.