Metal-based new sulfonamides: Design, synthesis, antibacterial, antifungal, and cytotoxic properties
Zahid H Chohan1, Hazoor A Shad
1Department of Chemistry, Bahauddin Zakariya University, Multan 60800, Pakistan. dr.zahidchohan@gmail.com
Abstract:
Cobalt(II), copper(II), nickel(II) and zinc(II) metal complexes with 5-chlorosalicyladehyde derived Schiff base sulfonamides have been synthesized and characterized. Structure and bonding nature of all the synthesized compounds have been deduced from physical, analytical, and spectral (IR, (1)H NMR, (13)C NMR, Mass, electronic) data. An octahedral geometry has been proposed for all the metal complexes. The ligands and their metal complexes have been screened for their in vitro antibacterial, antifungal, and cytotoxic properties and results are reported.
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