Related Experiment Video
Updated: May 30, 2026

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Facile fabrication of gold nanoparticle arrays for efficient surface-enhanced Raman scattering
Yuling Wang1, Hongjun Chen, Erkang Wang
1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Graduate School of the Chinese Academy of Sciences, Changchun, Jilin 130022, People's Republic of China.
Abstract:
An effective and facile method for the fabrication of a surface-enhanced Raman scattering (SERS)-active film with closely packed gold nanoparticle (AuNP) arrays is proposed by self-assembly of different sizes (16, 25, 40 and 70 nm) of AuNPs at a toluene/water interface with ethanol as the inducer. The as-prepared AuNP arrays exhibit efficient Raman scattering enhancement, and the enhancement factors estimated using p-aminothiophenol as a probe molecule range from 10(5) to 10(7). This is attributed to the coupling electromagnetic SERS enhancement mechanism with additional localization field within closely packed AuNPs, which have greater SERS activity and reproducibility than that on aggregates and on self-assembled monolayers of isolated AuNPs on glass.

