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Related Experiment Video

Updated: May 30, 2026

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice
11:32

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice

Published on: November 23, 2015

Multimode interference devices for focusing in microfluidic channels.

Hamish C Hunt1, James S Wilkinson

  • 1Optoelectronics Research Centre, University of Southampton, Southampton SO17 1BJ, UK.

Optics Letters
|August 18, 2011
PubMed
Summary
This summary is machine-generated.

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Multimode interference devices offer a cost-effective microlens alternative for microflow cytometry. These integrated optical microsystems enable high-resolution cell analysis in microfluidic channels.

Area of Science:

  • Optics and Photonics
  • Microfluidics
  • Biomedical Engineering

Background:

  • Automated optical microsystems are crucial for chemical analysis and cell identification.
  • Microflow cytometry requires integrated microlenses for high-resolution measurements within microfluidic channels.

Purpose of the Study:

  • To investigate multimode interference (MMI) devices as a simple and effective alternative to microlenses for microflow cytometry.
  • To design, realize, and integrate MMIs with microfluidic channels for enhanced optical microsystems.

Main Methods:

  • Utilized multimode interference (MMI) principles based on self-imaging in multimode waveguides.
  • Designed and fabricated MMIs integrated into silica-based glass waveguide microfluidic channels.

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Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Published on: June 12, 2015

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
09:54

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics

Published on: September 10, 2018

Related Experiment Videos

Last Updated: May 30, 2026

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice
11:32

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice

Published on: November 23, 2015

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique
10:12

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Published on: June 12, 2015

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
09:54

Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics

Published on: September 10, 2018

Main Results:

  • MMIs demonstrated effective focusing within microfluidic channels.
  • Achieved focal spot sizes of 2.4 μm at distances up to 43.7 μm into the channel.

Conclusions:

  • MMIs provide a viable, low-cost, and compact optical focusing solution for microflow cytometry.
  • This integration advances the development of high-resolution, automated optical microsystems for biological analysis.