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Updated: May 29, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Nuclear medicine and molecular imaging of the pediatric chest: current practical imaging assessment
Frederick D Grant1, S Ted Treves
1Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA. frederick.grant@childrens.harvard.edu
Insights
Pediatric nuclear medicine chest imaging is versatile, evaluating congenital issues, adult-like diseases, and cancers. Positron emission tomography (PET) significantly advanced pediatric oncology, especially for chest tumors.
Area of Science:
- Nuclear medicine
- Pediatric radiology
- Thoracic imaging
Background:
- Nuclear medicine studies in children's chests have diverse applications, differing from adult indications.
- These studies address congenital, developmental, and adult-type thoracic diseases in pediatric patients.
- Common applications include evaluating cardiac, pulmonary, aerodigestive, and oncologic conditions.
Purpose of the Study:
- To outline the broad spectrum of nuclear medicine applications in pediatric chest imaging.
- To highlight the utility of established radiopharmaceuticals and imaging techniques in children.
- To emphasize the impact of positron emission tomography (PET) on pediatric thoracic oncology.
Main Methods:
- Utilizes standard nuclear medicine radiopharmaceuticals and imaging protocols.
- Applies techniques for evaluating cardiac and pulmonary function and perfusion.
- Employs imaging for aerodigestive tract disorders and pediatric malignancies, including PET/CT.
Main Results:
- Nuclear medicine effectively evaluates a wide range of pediatric chest conditions.
- Techniques are comparable to those used in adult imaging.
- Positron emission tomography, particularly with 18F-FDG, has revolutionized pediatric chest cancer imaging.
Conclusions:
- Nuclear medicine is a crucial tool for diagnosing and managing pediatric chest diseases.
- The integration of PET has significantly enhanced the diagnostic capabilities in pediatric thoracic oncology.
- Pediatric nuclear medicine offers comprehensive evaluation for diverse thoracic pathologies.
Abstract:
In the chest, the indications for nuclear medicine studies are broader and more varied in children than in adults. In children, nuclear medicine studies are used to evaluate congenital and developmental disorders of the chest, as well as diseases more typical of adults. In the chest, pediatric nuclear medicine uses the same radiopharmaceuticals and imaging techniques as used in adults to evaluate cardiac and pulmonary disease, aerodigestive disorders, and pediatric malignancies. The introduction of PET (mostly using (18)F-FDG) has transformed pediatric nuclear oncology, particular for imaging malignancies in the chest.
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