Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Salivary Glands and Saliva01:23

Salivary Glands and Saliva

The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Extracellular Particles to Track Cancer Biomarkers from Tissue to Biofluids.

Journal of dental research·2025
Same author

Antarctic Krill with parasites grow slower than uninfected peers.

Marine biology·2025
Same author

Role of Saliva and Salivary Diagnostics in the Advancement of Oral Health.

Journal of dental research·2019
Same author

Defective NaCl Reabsorption in Salivary Glands of Eda-Null X-LHED Mice.

Journal of dental research·2018
Same author

Human tRNA-Derived Small RNAs Modulate Host-Oral Microbial Interactions.

Journal of dental research·2018
Same author

Liquid Biopsy in Head and Neck Cancer: Promises and Challenges.

Journal of dental research·2018

Related Experiment Video

Updated: May 29, 2026

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles
08:50

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles

Published on: October 10, 2013

Scientific frontiers: emerging technologies for salivary diagnostics.

B J Baum1, J R Yates, S Srivastava

  • 1Molecular Physiology and Therapeutics Branch, NIDCR, NIH, Bethesda, MD 20892, USA.

Advances in Dental Research
|September 16, 2011
PubMed
Summary

Saliva analysis has advanced into the

Area of Science:

  • Biomedical diagnostics and 'omics' research.

Background:

  • Saliva is a well-established biofluid with extensive biochemical and physiological data.
  • The 'omics' era has enabled comprehensive analysis of saliva's proteomic, genomic, and microbiome components.

Purpose of the Study:

  • To highlight the translational potential of salivary constituents for personalized medicine.
  • To emphasize the role of salivary diagnostics, particularly in early cancer detection.
  • To introduce the Salivaomics Knowledge Base (SKB) as a key resource for salivary biomarker dissemination.

Main Methods:

  • Comprehensive deciphering of salivary proteomic, genomic, and microbiome constituents.
  • Leveraging the Salivaomics Knowledge Base (SKB) for data dissemination.
  • Focus on translational and clinical applications of salivary biomarkers.

More Related Videos

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots
11:11

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots

Published on: February 11, 2022

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens
09:08

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens

Published on: September 12, 2016

Related Experiment Videos

Last Updated: May 29, 2026

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles
08:50

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles

Published on: October 10, 2013

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots
11:11

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots

Published on: February 11, 2022

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens
09:08

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens

Published on: September 12, 2016

Main Results:

  • Salivary 'omics' data is being translated into personalized medical applications.
  • Early cancer detection is a significant emerging application for salivary diagnostics.
  • Dedicated resources like SKB are central to advancing salivary diagnostics.

Conclusions:

  • Saliva is a rapidly advancing frontier in diagnostics, moving beyond traditional analysis.
  • The integration of 'omics' data is unlocking novel diagnostic and clinical utilities for saliva.
  • Salivaomics Knowledge Base (SKB) plays a crucial role in realizing the potential of salivary biomarkers.