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Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
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Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Myasthenia Gravis ll: Pathophysiology01:22

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The disease process of myasthenia gravis begins at the neuromuscular junction, where antibodies attack key proteins needed for muscle activation. This immune reaction weakens signal transmission, leading to the characteristic muscle fatigue and weakness that define the condition.Immune-Mediated DamageIn most individuals, antibodies target acetylcholine receptors (AChRs) on the postsynaptic membrane of muscle cells. By blocking acetylcholine binding, these antibodies prevent the nerve signal...
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Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
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Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy
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Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy

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Pyomyositis.

Vikas Agarwal1, Sandeep Chauhan, Rakesh K Gupta

  • 1Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India. vikasagr@sgpgi.ac.in

Neuroimaging Clinics of North America
|October 29, 2011
PubMed
Summary
This summary is machine-generated.

Pyomyositis, a primary skeletal muscle infection often caused by Staphylococcus aureus, is increasingly reported globally. Early diagnosis via MR imaging and prompt treatment ensure favorable outcomes for patients.

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Last Updated: May 28, 2026

Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy
10:55

Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy

Published on: October 31, 2025

Area of Science:

  • Infectious Diseases
  • Musculoskeletal Disorders
  • Radiology

Background:

  • Pyomyositis is a primary skeletal muscle infection, prevalent in tropics but increasingly seen worldwide.
  • It affects both immunocompromised and immunocompetent individuals.
  • Staphylococcus aureus is the most frequent causative pathogen.

Purpose of the Study:

  • To highlight the diagnostic utility of MR imaging in pyomyositis.
  • To emphasize the importance of early diagnosis and treatment for favorable outcomes.

Main Methods:

  • Review of pyomyositis epidemiology, causative organisms, and diagnostic standards.
  • Evaluation of noninvasive diagnostic methods, focusing on Magnetic Resonance (MR) imaging.
  • Discussion of treatment strategies including antibiotics and surgical drainage.

Main Results:

  • Muscle histology and culture are gold standards for diagnosis.
  • MR imaging is a highly sensitive noninvasive method for detecting pyomyositis, including subclinical cases.
  • Early diagnosis and appropriate management are crucial for a positive prognosis.

Conclusions:

  • Pyomyositis requires prompt diagnosis and treatment.
  • MR imaging offers significant advantages for noninvasive pyomyositis detection.
  • Effective management involves antibiotics and, when necessary, pus drainage.