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Updated: May 28, 2026

Fluorescent Dye Labeling of Erythrocytes and Leukocytes for Studying the Flow Dynamics in Mouse Retinal Circulation
Published on: July 3, 2017
[Ocular findings in hematological diseases]
1Klinik für Augenheilkunde, Universitätsklinikum Ulm, Prittwitzstr. 43, 89075 Ulm. sekretariat.augenklinik@uniklinik-ulm.de
Ocular manifestations occur in up to 90% of patients with hematological diseases, often presenting as the first symptom. Prompt diagnosis is crucial, especially when eye findings like retinal changes are the initial sign.
Area of Science:
- Ophthalmology
- Hematology
- Internal Medicine
Context:
- Hematological diseases frequently manifest in the eyes, affecting up to 90% of patients.
- Ocular findings can be the initial, often asymptomatic, presenting symptom of underlying blood disorders.
- Diagnosis can be challenging when eye conditions are the first indicator of a hematological disease.
Purpose:
- To highlight the significant association between hematological disorders and ocular manifestations.
- To emphasize the diagnostic importance of ophthalmological findings in hematological diseases.
- To guide clinicians in considering hematological conditions in patients with unexplained retinal alterations.
Summary:
- Conjunctival and retinal involvement are common in hematological conditions such as anemia, leukemia, lymphomas, myeloproliferative/myelodysplastic syndromes, and coagulopathies.
- Opportunistic infections secondary to hematological diseases can also cause ocular symptoms.
- Unexplained retinal changes, including hemorrhages and cotton-wool spots, necessitate exclusion of an underlying hematological disease.
Impact:
- Enhances early diagnosis of hematological diseases through recognition of ocular signs.
- Improves patient outcomes by integrating ophthalmological and hematological care.
- Raises awareness among clinicians regarding the crucial link between eye health and blood disorders.
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