Related Experiment Video
Updated: May 27, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Rational antibiotic treatment can be achieved through audits and teaching]
Lars Bjerrum1, Bente Gahrn-Hansen, Hans Jørn Kolmos
1Institut for Folkesundhedsvidenskab, Afdeling for Almen Medicin og Forskningsenheden for Almen Praksis, Københavns Universitet, Øster Farimagsgade 5, 1014 København K, Denmark. lbjerrum@sund.ku.dk
Abstract:
A prerequisite for rational antibiotic treatment is the suspicion that the disease is caused by bacteria and that treatment will reduce symptoms and complications. In primary health care most infections are caused by bacteria. The European project HAPPY AUDIT found that an intervention targeting doctors and patients in primary care led to a considerable decrease in antibiotic prescribing. Teaching of hospital doctors, combined with a restriction in the choice of antibiotics, resulted in a decrease in multidrug-resistant strains. A concerted effort is needed to curb the growing resistance problem.
More Related Videos
Related Concept Videos
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Microbiota Modulation by Antibiotics
Mechanism of Antibiotic Resistance in MRSA
Acute Pyelonephritis II: Diagnostic Studies and Management
Clinical Significance of Antibiotic Resistance
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

