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Updated: May 27, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Phrenic nerve stimulation with the quadripolar left ventricular lead not overcome by 'electronic repositioning'
Senthil Kirubakaran1, Christopher A Rinaldi
1Guys and St Thomas NHS Trust, London, UK. senthilk1uk@yahoo.co.uk
Abstract:
Phrenic nerve stimulation (PNS) is a frequent occurrence in patients implanted with a cardiac resynchronization therapy (CRT) device. The quadripolar left ventricular offers 10 pacing configurations which can overcome PNS in most cases. We report a rare case of significant PNS following upgrade to a CRT which was present with all 10 pacing configurations one day following implantation which required lead repositioning.
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