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Updated: May 27, 2026

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)
Published on: April 7, 2021
[Extracorporeal membrane oxygenation of a child with severe chemical pneumonia]
Anders Bastholm Bille1, Karen Damgaard Pedersen, Steen Hertel
1Anæstesi- og Operationsklinikken, Juliane Marie Centret, Rigshospitalet, Denmark. andersbbille@dadlnet.dk
Insights
A child with severe respiratory distress after lamp oil ingestion improved with extracorporeal membrane oxygenation (ECMO). This life support technology was crucial for recovery, leading to a normal lung X-ray post-treatment.
Area of Science:
- Pediatric Critical Care Medicine
- Toxicology
- Respiratory Medicine
Background:
- Hydrocarbon ingestion, such as lamp oil, can cause severe acute respiratory distress syndrome (ARDS) in children.
- Standard mechanical ventilation strategies may be insufficient for managing severe hydrocarbon-induced ARDS.
Observation:
- A 13-month-old child ingested lamp oil, leading to severe ARDS, pneumothorax, and emphysema.
- Initial mechanical ventilation, including high-frequency oscillation, failed to stabilize the patient's condition.
Findings:
- Veno-arterial extracorporeal membrane oxygenation (ECMO) was initiated on day three and provided life support for nine days.
- Following ECMO and two additional days of conventional ventilation, the child was successfully extubated.
- Four months post-treatment, the child showed normal lung X-rays and no residual disease signs.
Implications:
- ECMO can be a life-saving intervention for pediatric patients with severe, refractory hydrocarbon-induced respiratory failure.
- This case highlights the potential severity of lamp oil ingestion and the critical role of advanced respiratory support.
- Successful ECMO treatment can lead to complete recovery in pediatric ARDS patients.
Abstract:
This case presents a thirteen months old child with severe acute respiratory distress syndrome after ingestion of lamp oil (hydrocarbon). Mechanical ventilation including high-frequency oscillation could not stabilise the course, and the child developed pneumothorax and emphysema. Treatment was changed to veno-arterial extracorporeal membrane oxygenation (ECMO) on the third day. After nine days of ECMO and further two days of conventional ventilatory treatment he was extubated, and four months later the child presented with normal X-ray of the lungs and without any signs of disease.
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