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Updated: May 27, 2026
07:34
Intravital Microscopy of the Inguinal Lymph Node
Published on: April 4, 2011
Pigmented lesion in the inguinal region.
Nadia El Fekih1, Abdelmooti Hawiloo, Soumeya Remmah
1Charles Nicolle Hospital Tunis, Tunis, Tunisia.
Dermatology Online Journal
|December 6, 2011
Summary
Pigmented Bowen disease (PBD), a rare skin cancer, presents as a dark brown plaque. Histopathology confirmed PBD, an unusual squamous cell carcinoma in situ, distinct from melanoma.
Area of Science:
- Dermatology
- Oncology
Background:
- Pigmented Bowen disease (PBD) is a rare variant of squamous cell carcinoma in situ.
- It is characterized by epidermal atypia and increased melanin pigment.
Observation:
- A 60-year-old woman presented with a 6-month history of a gradually enlarging, solitary, dark brown plaque in the right inguinal region.
- Clinical presentation suggested a pigmented skin lesion.
Findings:
- Histopathological examination revealed hyperkeratosis, parakeratosis, acanthosis, epidermal architectural disorganization, and atypical keratinocytes.
- Increased melanin pigment in the papillary dermis was noted, confirming the diagnosis of PBD.
Implications:
- Complete surgical resection confirmed the diagnosis of PBD.
- Differential diagnoses for PBD include pigmented basal cell carcinoma and superficial spreading melanoma.
- Accurate diagnosis is crucial for appropriate management of this rare skin malignancy.
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