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Related Experiment Video

Updated: May 26, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

[Quantitative white matter analysis by diffusion tensor imaging and potential functional correlation].

Kenichi Oishi¹, Susumu Mori

¹Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, MD, USA.

Brain and Nerve = Shinkei Kenkyu No Shinpo

|December 8, 2011

Summary

This summary is machine-generated.

Diffusion tensor imaging (DTI) measures water diffusion in the brain to map white matter anatomy. This MRI technique aids in understanding brain function and disease by analyzing fiber tracts.

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Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

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Published on: September 12, 2011

Area of Science:

Neuroimaging
Biophysics
Medical Physics

Context:

Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging (MRI) technique.
It measures water molecule diffusion to infer tissue microstructure.
Brain anatomy, particularly white matter, restricts water diffusion, providing insights into neural structures.

Purpose:

To explore the utility of Diffusion Tensor Imaging (DTI) for in vivo human white matter anatomy investigation.
To discuss quantitative and qualitative DTI analysis methods for studying brain function, development, and disease.
To review existing DTI analysis techniques and their limitations, such as Voxel-Based Analysis (VBA).

Summary:

DTI combines water diffusion measurements with a tensor model to create directional maps of axonal fiber bundles.
Quantitative DTI analysis allows investigation of white matter anatomy's relationship with brain function and identification of alterations in development or disease.
Alternative analysis methods like tract-based spatial statistics and atlas-based analysis are presented to overcome VBA limitations.

Impact:

DTI provides crucial directional information for mapping white matter tracts in vivo.
Quantitative DTI analysis facilitates research into brain connectivity, function, and pathology.
Future research combining DTI with resting-state fMRI promises a comprehensive view of human brain connectivity.