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Related Concept Videos

Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: May 26, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Myocardial perfusion acquisition without magnetization preparation or gating.

Edward V R DiBella1, Liyong Chen, Matthias C Schabel

  • 1Utah Center for Advanced Imaging Research, Department of Radiology, University of Utah, Salt Lake City, Utah, USA. edward.dibella@hsc.utah.edu

Magnetic Resonance in Medicine
|December 23, 2011
PubMed
Summary
This summary is machine-generated.

A new ungated, steady-state myocardial perfusion MRI method using spoiled gradient echo (SPGR) acquisition shows comparable signal to standard methods. This approach may enable cine cardiac perfusion and improve signal-to-noise ratio efficiency.

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MRI and PET in Mouse Models of Myocardial Infarction
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MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

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Last Updated: May 26, 2026

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06:29

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Published on: June 11, 2019

MRI and PET in Mouse Models of Myocardial Infarction
10:46

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

Area of Science:

  • Cardiovascular Imaging
  • Magnetic Resonance Imaging (MRI)
  • Medical Physics

Background:

  • Current myocardial perfusion MRI relies on saturation recovery sequences to mitigate arrhythmia sensitivity.
  • This limits acquisition speed and can impact signal-to-noise ratio (SNR).

Purpose of the Study:

  • To introduce and evaluate a novel ungated, steady-state spoiled gradient echo (SPGR) acquisition for myocardial perfusion MRI.
  • To compare its performance against conventional saturation recovery sequences.

Main Methods:

  • Developed an ungated, steady-state SPGR sequence without a saturation pulse.
  • Utilized rapid, undersampled readouts and advanced reconstruction techniques for continuous data acquisition.
  • Validated through simulations and phantom experiments, comparing contrast and signal with standard methods.
  • Retrospective electrocardiogram (ECG) or self-gating can be applied.

Main Results:

  • Simulations and phantom measurements demonstrated comparable signal and contrast between the proposed SPGR method and standard saturation recovery.
  • Achieved similar signal levels across a range of T(1) values relevant to myocardial tissue concentrations with specific parameters (14° flip angle, 80 ms saturation recovery time).
  • Preliminary in-subject data suggest the potential of this new approach.

Conclusions:

  • The proposed ungated, steady-state SPGR acquisition is a viable alternative to conventional saturation recovery for myocardial perfusion MRI.
  • This technique holds promise for enabling cine cardiac perfusion imaging.
  • It offers potential for improved SNR efficiency in myocardial perfusion MRI acquisitions.