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Updated: May 26, 2026
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Robotic-assisted Lateral Pancreaticojejunostomy for Chronic Pancreatitis
Published on: September 5, 2025
Current surgical treatment for chronic pancreatitis
Takayuki Aimoto1, Eiji Uchida, Yoshiharu Nakamura
1Surgery for Organ Function and Biological Regulation, Nippon Medical School, Tokyo, Japan. aimoto@nms.ac.jp
Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi
|December 27, 2011
Summary
Chronic pancreatitis (CP) surgery requires individualized approaches. Hybrid procedures, like the Frey procedure, are now preferred for long-term pain relief and managing complications in CP patients.
Area of Science:
- Gastroenterology and Surgical Management
Background:
- Chronic pancreatitis (CP) is a benign inflammatory condition characterized by multifactorial pain mechanisms.
- Pain theories include neurogenic factors and increased intraductal/intraparenchymal pressures, supported by drainage procedure efficacy.
- Contributing factors to pain involve pancreatic ischemia, central sensitization, and complications like pseudocysts or stenosis.
Purpose of the Study:
- To review the surgical management of chronic pancreatitis (CP).
- To evaluate the efficacy of different surgical approaches, particularly hybrid procedures, for pain relief and complication management in CP.
Main Methods:
- Historical classification of surgical procedures into decompression, resection, denervation, and hybrid categories.
- Review of the shift from traditional resections (pancreaticoduodenectomy) to modern hybrid procedures (e.g., Frey procedure).
Main Results:
- Hybrid procedures, including duodenum-preserving pancreatic head resection and the Frey procedure, demonstrate safety and effectiveness.
- These hybrid approaches provide long-term pain relief and successfully treat CP-related complications.
Conclusions:
- Hybrid procedures are recommended as the primary surgical option for patients with chronic pancreatitis.
- Individualized surgical management based on multifactorial pain mechanisms is crucial for optimal patient outcomes.
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